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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
7.88
Human Site:
S165
Identified Species:
11.56
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
S165
P
E
S
P
L
N
A
S
Y
V
Y
K
E
H
P
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
S165
P
E
S
P
L
N
A
S
Y
V
Y
K
E
H
P
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
Dog
Lupus familis
XP_537128
620
68704
L166
P
E
S
P
L
N
T
L
Y
V
Y
K
E
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
F165
P
E
S
P
L
D
A
F
Y
V
Y
K
E
H
P
Rat
Rattus norvegicus
Q66HG7
589
65047
F165
P
E
S
P
L
D
A
F
Y
V
Y
K
E
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
K155
R
D
K
E
E
G
L
K
P
V
I
S
E
P
Q
Chicken
Gallus gallus
XP_422189
625
69278
T170
E
E
S
H
L
L
N
T
A
Y
F
Y
K
D
H
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
Q292
V
L
E
P
V
D
H
Q
K
I
Q
Y
E
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
G218
A
I
E
I
F
S
S
G
I
A
S
G
I
H
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
S32
P
R
P
I
V
S
F
S
K
N
Q
R
W
P
D
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
Q140
E
K
L
L
H
N
I
Q
T
L
G
Y
D
M
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
L122
C
G
L
P
P
K
L
L
L
N
L
E
T
A
G
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
P159
P
I
L
D
F
S
S
P
P
L
D
E
L
L
M
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
H258
Q
R
K
N
L
G
K
H
W
S
E
K
K
L
E
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
0
86.6
N.A.
86.6
86.6
N.A.
13.3
20
0
13.3
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
0
86.6
N.A.
93.3
93.3
N.A.
20
40
0
33.3
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
13.3
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
33.3
N.A.
N.A.
13.3
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
25
0
7
7
0
0
0
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
19
0
0
0
0
7
0
7
7
7
% D
% Glu:
13
38
13
7
7
0
0
0
0
0
7
13
44
0
7
% E
% Phe:
0
0
0
0
13
0
7
13
0
0
7
0
0
0
13
% F
% Gly:
0
7
0
0
0
13
0
7
0
0
7
7
0
0
7
% G
% His:
0
0
0
7
7
0
7
7
0
0
0
0
0
38
7
% H
% Ile:
0
13
0
13
0
0
7
0
7
7
7
0
7
0
0
% I
% Lys:
0
7
13
0
0
7
7
7
13
0
0
38
13
0
0
% K
% Leu:
0
7
19
7
44
7
13
13
7
13
7
0
7
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
7
0
25
7
0
0
13
0
0
0
0
0
% N
% Pro:
44
0
7
44
7
0
0
7
13
0
0
0
0
19
38
% P
% Gln:
7
0
0
0
0
0
0
13
0
0
13
0
0
0
7
% Q
% Arg:
7
13
0
0
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
38
0
0
19
13
19
0
7
7
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
7
7
0
0
0
7
0
0
% T
% Val:
7
0
0
0
13
0
0
0
0
38
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
32
7
32
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _